Iocarmic acid
Iocarmic acid is a myelographic contrast agent. Iocarmic acid is used for lumbar nerve root angiography and ventriculography. Iocarmic acid induces arachnoiditis via lumbar subarachnoid injection. Iocarmic acid can be used for the research of arachnoiditis.
For research use only. We do not sell to patients.
- CAS No.: 10397-75-8
- Formula: C24H20I6N4O8
- Molecular Weight:1253.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Macaque monkeys (5-7 kg)[1]
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Dosage:1.2 mL of 282 mg I/mL
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Administration:intrathecal; single injection
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Result:Induced a consistent myelographic arachnoiditis score of 36 (maximum possible score) across all 4 animals tested.
Produced an average histologic arachnoiditis score of 18, with individual scores ranging from 12 to 20.
Resulted in scores significantly higher than scores for iopamidol, metrizamide, and CSF controls (P < 0.05, Wilcoxon test).
Chemical Information
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CAS No. 10397-75-8
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Molecular Weight 1253.86
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Formula C24H20I6N4O8
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SMILES
O=C(C1=C(C(NC(CCCCC(NC2=C(I)C(C(NC)=O)=C(I)C(C(O)=O)=C2I)=O)=O)=C(C(C(NC)=O)=C1I)I)I)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Iocarmic acid Related Classifications
HY-182568 Related Classifications
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