IP receptor antagonist 1
CAY10449 is an I prostanoid receptor antagonist. CAY10449 can reverse iloprost-induced TEER reduction. CAY10449 can also reverse the effect of ONO-1301 in mouse model. CAY10449 can be studied in research on athsma and allergic airway inflammation.
For research use only. We do not sell to patients.
- Formula: C19H21N3O2
- Molecular Weight:323.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 323.39
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Formula C19H21N3O2
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SMILES
CC(OC1=CC=C(C(C2=CC=C(NC3=NCCN3)C=C2)=O)C=C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tasha R Womac, et al., Prostacyclin as a Negative Regulator of Angiogenesis in the Neurovasculature.
[2]. Hayashi, M., et al., (2010). A prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 40(2), 317-326. [Content Brief]
[3]. Kuo, C. H., et al., (2010). Prostaglandin I(2) analogues enhance growth-related oncogene-alpha expression in human monocyte-derived dendritic cells. Inflammation, 33(5), 334-343. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)