Isoarundinin I
Isoarundinin I is a stilbene compound that can be isolated from Arundinu bambusifolia.
For research use only. We do not sell to patients.
- CAS No.: 151538-57-7
- Formula: C22H22O4
- Molecular Weight:350.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| ADR5000 cell line | IC50 |
60.42 μM
Compound: 1
|
Cytotoxicity against human CEM/ADR5000 cells overexpressing P-gp assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay
Cytotoxicity against human CEM/ADR5000 cells overexpressing P-gp assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay
|
[PMID: 36538372] |
| CCRF-CEM | IC50 |
43.36 μM
Compound: 1
|
Cytotoxicity against human CCRF-CEM cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay
Cytotoxicity against human CCRF-CEM cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay
|
[PMID: 36538372] |
| Neutrophil | IC50 |
1.7 μM
Compound: 34
|
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
|
[PMID: 27525452] |
| Neutrophil | IC50 |
2.8 μM
Compound: 34
|
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
|
[PMID: 27525452] |
Chemical Information
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CAS No. 151538-57-7
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Molecular Weight 350.41
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Formula C22H22O4
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SMILES
OC1=CC=C(CC2=C(CCC3=CC(O)=CC=C3)C=C(O)C=C2OC)C=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)