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Cat. No.: HY-N21985

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Camptothecoside

Camptothecoside is a novel indole glycoside isolated from the fruits of Camptotheca acuminata, and it serves as a biosynthetic intermediate of camptothecin. Camptothecoside shares the same four-ring conjugated system (rings A-D) as camptothecin, but it has a ketal glycoside structure (ring E) at the C-21 position, with a β-D-glucopyranosyl group linked to the C-21 position. Camptothecoside can be used in studies on camptothecin biosynthesis and natural product chemistry.

For research use only. We do not sell to patients.

CAS No.: 1914972-40-9
Formula: C₂₆H₂₆N₂O₈
Molecular Weight:494.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Camptothecoside Chemical Structure

CAS No.: 1914972-40-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

In Vitro

Camptothecoside (50 μM; 48 h) exhibits weak in vitro cytotoxicity against human hepatoma HepG2, human breast carcinoma MCF-7, and human osteosarcoma U2-OS cells at a concentration of 50 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

human hepatoma HepG2 cells, human breast carcinoma MCF-7 cells, human osteosarcoma U2-OS cells
Concentration:

50 μM
Incubation Time:

48 h
Result:

Showed weak cytotoxicity against all three tested cell lines at the highest tested concentration of 50 μM.

Chemical Information

CAS No. 1914972-40-9
Molecular Weight 494.49
Formula C₂₆H₂₆N₂O₈
SMILES

O=C1N2C(C3=NC4=CC=CC=C4C=C3C2)=CC5=C1CO[C@H]([C@@H]5C=C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang P, et al. New indole glucosides as biosynthetic intermediates of camptothecin from the fruits of Camptotheca acuminata. Fitoterapia. 2015 Jun;103:1-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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