Srcin1 - SRC kinase signaling inhibitor 1 Gene

Also Known as P140; SNIP; p140Cap; mKIAA1684

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56013

Summary

Predicted to enable protein domain specific binding activity and protein kinase binding activity. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (Src kinase signaling inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Srcin1 Products (1)

mRNA Protein Name
NM_018873.2 NP_061361.2 SRC kinase signaling inhibitor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14657239 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cell adhesion IDA
IDA: Inferred from direct assay
14657239 MGI
involved in regulation of synapse assembly IDA
IDA: Inferred from direct assay
28641114 MGI
involved in regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
28641114 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28641114 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28641114 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
29161354 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SRC kinase signaling inhibitor 1

  • Snap-25-interacting protein

  • p130Cas-associated protein

Srcin1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Srcin1 Q9QWI6 BCAR1 Homo sapiens P56945
Anti Bait CoIP
14657239
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16905 T338C Src-IN-1 Inhibitor / Unkown
HY-RS13753 SRCIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srcin1 NCBI NCBI:80725