Imdevimab
Based on 1 publication(s) in Google Scholar
Imdevimab (REGN10987) is a human monoclonal antibody that targets SARS-CoV-2 virus. Imdevimab can be used in combination with Casirivimab (HY-P99341) to reduce viral load and transiently increases anti-receptor-binding domain IgG titers. Imdevimab maintains most of its neutralization activity against viruses with B.1.1.7, B.1.351 and mink cluster 5 spike proteins.
For research use only. We do not sell to patients.
- Purity: 95.00%
- CAS No.: 2415933-40-1
- Molecular Weight:144.14 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Imdevimab
More
Biological Activity
Human IgG1 lambda2
Virus
SARS-CoV-2
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
YP_009724390.1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG1 lambda2
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2415933-40-1
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Appearance Liquid
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Molecular Weight 144.14 kDa
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Color Colorless to light yellow
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SMILES
[Imdevimab]
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Synonyms
REGN10987
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Commun Biol
2025 Jul 21;8(1):1082. PMID: 40691508
Purity & Documentation
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. Casirivimab. 2022 May 15. [Content Brief]
[2]. Tada, T., et al., (2021). Decreased neutralization of SARS-CoV-2 global variants by therapeutic anti-spike protein monoclonal antibodies. bioRxiv : the preprint server for biology, 2021.02.18.431897. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Imdevimab Related Classifications
HY-P99342 Related Classifications
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