JS11
Based on 1 Customer Validation
JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models.
For research use only. We do not sell to patients.
- Purity: 99.22%
- CAS No.: 1394592-04-1
- Formula: C23H28N4O3
- Molecular Weight:408.49
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 1394592-04-1
-
Appearance Solid
-
Molecular Weight 408.49
-
Formula C23H28N4O3
-
Color White to off-white
-
SMILES
O=C(C1=CC=C2C(N(CC3CC3)C(N2C4CCCCC4)=O)=C1)NCC5=CC(C)=NO5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (122.40 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4480 mL | 12.2402 mL | 24.4804 mL | 61.2010 mL |
| 5 mM | 0.4896 mL | 2.4480 mL | 4.8961 mL | 12.2402 mL | |
| 10 mM | 0.2448 mL | 1.2240 mL | 2.4480 mL | 6.1201 mL | |
| 15 mM | 0.1632 mL | 0.8160 mL | 1.6320 mL | 4.0801 mL | |
| 20 mM | 0.1224 mL | 0.6120 mL | 1.2240 mL | 3.0601 mL | |
| 25 mM | 0.0979 mL | 0.4896 mL | 0.9792 mL | 2.4480 mL | |
| 30 mM | 0.0816 mL | 0.4080 mL | 0.8160 mL | 2.0400 mL | |
| 40 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5300 mL | |
| 50 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2240 mL | |
| 60 mM | 0.0408 mL | 0.2040 mL | 0.4080 mL | 1.0200 mL | |
| 80 mM | 0.0306 mL | 0.1530 mL | 0.3060 mL | 0.7650 mL | |
| 100 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6120 mL |
JS11 Related Classifications
HY-153650 Related Classifications
Powered by Bioz