YM-1758735
YM-1758735 is an orally active androgen receptor (AR) antagonist with an IC50 of 0.2 μM. YM-1758735 inhibits AR-mediated transcriptional activation. YM-1758735 can be used for the research of prostate.
For research use only. We do not sell to patients.
- CAS No.: 262294-30-4
- Formula: C21H19F5N4O
- Molecular Weight:438.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
YM-1758735 (Compound 85) inhibits AR-mediated transcriptional activation with an IC50 of 0.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar (male)[1]
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Dosage:10 mg/kg
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Administration:p.o.; daily; 15 days
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Result:Failed to decrease ventral prostate weight.
Chemical Information
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CAS No. 262294-30-4
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Molecular Weight 438.40
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Formula C21H19F5N4O
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SMILES
C[C@@H]1N(C2=CC(C(F)(F)F)=C(C#N)C=C2)C[C@@H](C)N(C(NC3=C(F)C=C(F)C=C3)=O)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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