ITE (Standard)
ITE (Standard) is the analytical standard of ITE. This product is intended for research and analytical applications. ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 448906-42-1
- Formula: C14H10N2O3S
- Molecular Weight:286.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 448906-42-1
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Molecular Weight 286.31
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Formula C14H10N2O3S
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SMILES
O=C(C1=CSC(C(C2=CNC3=C2C=CC=C3)=O)=N1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Song J, et al. A ligand for the aryl hydrocarbon receptor isolated from lung. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14694-9. [Content Brief]
[2]. Nugent LF, et al. ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity. Invest Ophthalmol Vis Sci. 2013 Nov 13;54(12):7463-9. [Content Brief]
[3]. Pang LP, et al. ITE inhibits growth of human pulmonary artery endothelial cells. Exp Lung Res. 2017 Oct;43(8):283-292. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)