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Cat. No.: HY-49924

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JNK-IN-26

JNK-IN-26 (JNK-IN-11) is a JNK inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2727965-47-9
Formula: C₃₆H₃₂N₈O₂
Molecular Weight:608.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

JNK-IN-26 Chemical Structure

CAS No.: 2727965-47-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

JNK-IN-26 (JNK-IN-11) is a JNK inhibitor^[1].

All JNK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	0.009 μM Compound: 73	Inhibition of JNK3-mediated c-jun phosphorylation in human A375 cells after 1 hr incubation Inhibition of JNK3-mediated c-jun phosphorylation in human A375 cells after 1 hr incubation	[PMID: 25415535]
HeLa	IC₅₀	0.048 μM Compound: 73	Inhibition of JNK3-mediated c-jun phosphorylation in human HeLa cells after 1 hr incubation Inhibition of JNK3-mediated c-jun phosphorylation in human HeLa cells after 1 hr incubation	[PMID: 25415535]

Chemical Information

CAS No. 2727965-47-9
Molecular Weight 608.69
Formula C₃₆H₃₂N₈O₂
SMILES

O=C(C1=CC(NC(/C=C/CN(C)C)=O)=CC=C1)NC(C=C2)=CC=C2NC3=NC=CC(C4=C(C=CC=C5)N5N=C4C6=CC=CC=C6)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Susan GHIASSIAN, et al. Methods and systems for personalized therapies. WO2022271717 A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
Purity & Documentation
References

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JNK-IN-26

All JNK Isoforms