Cannabidiol-C4
Cannabidiol-C4 (CBD-C4) is a phytocannabinoid analog. Cannabidiol-C4 attenuates electrostimulation-induced tonic convulsions and reverses NMDA receptor antagonist-induced social interaction deficits. Cannabidiol-C4 can be used in research on epilepsy and schizophrenia.
For research use only. We do not sell to patients.
- CAS No.: 60113-11-3
- Formula: C20H28O2
- Molecular Weight:300.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| BV-2 | IC50 |
11.1 μM
Compound: 12c
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Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability by crystal violet staining based assay
Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability by crystal violet staining based assay
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[PMID: 37531582] |
| BV-2 | IC50 |
5 μM
Compound: 12c
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Anti-neuroinflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by microplate reader analysis
Anti-neuroinflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by microplate reader analysis
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[PMID: 37531582] |
In Vivo
Cannabidiol-C4 (3-30 mg/kg; intraperitoneal injection; single acute administration 60 minutes before the social interaction test) ameliorates subchronic NMDA receptor antagonist-induced social interaction deficits in female Lister Hooded rats[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Epilepsy mouse model[2]
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Dosage:3, 10, 30, 100, and 200 mg/kg
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Administration:i.p.; single administration 60 minutes before MES
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Result:At 100 and 200 mg/kg, the number of mice showing tonic convulsions decreased by 100% compared with vehicle controls.
No effect was observed at 3, 10, or 30 mg/kg.
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Animal Model:Lister Hooded (female)[2]
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Dosage:3, 10, and 30 mg/kg
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Administration:i.p.; single acute administration 60 minutes before social interaction test
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Result:At 30 mg/kg, sniffing behaviour and following behaviour increased and avoidance behaviour decreased in sub-chronic NMDA receptor antagonist-treated rats.
At 3 and 10 mg/kg, no effect was observed on any measured social interaction parameter.
No effect was observed on object exploration or locomotor activity (line crossings).
Chemical Information
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CAS No. 60113-11-3
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Appearance Solid
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Molecular Weight 300.44
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Formula C20H28O2
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Color White to off-white
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SMILES
CC([C@H]1[C@H](C2=C(C=C(C=C2O)CCCC)O)C=C(CC1)C)=C
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Synonyms
CBD-C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (279 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cannabidiol-C4 Related Classifications
HY-169452 Related Classifications
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