Regorafenib (Standard)
Regorafenib (Standard) is the analytical standard of Regorafenib. This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 755037-03-7
- Formula: C21H15ClF4N4O3
- Molecular Weight:482.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 755037-03-7
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Molecular Weight 482.82
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Formula C21H15ClF4N4O3
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SMILES
O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F
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Synonyms
BAY 73-4506 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Regorafenib (Standard) Related Classifications
HY-10331R Related Classifications
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Keywords
- Regorafenib (Standard)
- 755037-03-7
- BAY 73-4506 (Standard)
- Reference Standards
- VEGFR
- Autophagy
- PDGFR
- Raf
- RET
- c-Kit
- FGFR
- Tie
- Vascular endothelial growth factor receptor
- Platelet-derived growth factor receptor
- Raf kinases
- SCFR
- CD117
- Fibroblast growth factor receptor
- Angiopoietin receptor
- Antitumorigenic
- antiangiogenic
- tumor
- HUVECs
- Hep3B cell
- HAoSMCs
- NIH-3T3
- Colo-205
- MDA-MB-231
- 786-O
- Inhibitor
- inhibitor
- inhibit