Saccharic acid
Based on 1 Customer Validation
Saccharic acid is a competitive and potent inhibitor of β-glucuronidase. Saccharic acid inhibits glucuronide synthesis. Saccharic acid as an efficient iron chelate to enhance photo-Fenton
degradation of organic contaminants.
For research use only. We do not sell to patients.
- Purity: 98.73%
- CAS No.: 87-73-0
- Formula: C6H10O8
- Molecular Weight:210.14
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
degradation of organic contaminants[2].
Saccharic acid (50 µM Fe (III)-saccharic acid90 min UV-C irradiation) enhances photo-Fenton degradation of methylene blue[1].
Saccharic acid (50-150 x 10-4 M; 1 h) potently, competitively, and reversibly inhibits β-glucuronidase activity from mouse liver and mouse kidney[2].
Saccharic acid (1×10-3 M; 2 h) strongly inhibits hydrolysis of o-aminophenylglucuronide by mouse liver β-glucuronidase preparations[2].
Saccharic acid (0.01 M; 90 min) reduces β-glucuronidase activity in intact mouse liver slices[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Saccharic acid (2 g/kg; intraperitoneal injection; daily; 3 weeks) or (3%; dietary supplementation; ad libitum; 3 weeks) does not alter normal growth in infant mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Infant mice[2]
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Dosage:2 g/kg (injection); 3% (dietary)
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Administration:intraperitoneal injection; daily; 3 weeks; dietary supplementation; ad libitum; 3 weeks
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Result:Showed no effect on normal growth, with animal weights identical to control values.
Chemical Information
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CAS No. 87-73-0
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Appearance Solid
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Molecular Weight 210.14
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Formula C6H10O8
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Color White to off-white
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SMILES
[C@H]([C@@H]([C@H](C(=O)O)O)O)([C@@H](C(=O)O)O)O
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 250 mg/mL (1189.68 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
[1]. Subramanian G, et al. Introducing saccharic acid as an efficient iron chelate to enhance photo-Fenton degradation of organic contaminants. Water Res. 2016;104:168-177. [Content Brief]
[2]. Karunairatnam M C, et al. The inhibition of β-glucuronidase by saccharic acid and the role of the enzyme in glucuronide synthesis[J]. Biochemical Journal, 1949, 44(5): 599. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.7587 mL | 23.7937 mL | 47.5873 mL | 118.9683 mL |
| 5 mM | 0.9517 mL | 4.7587 mL | 9.5175 mL | 23.7937 mL | |
| 10 mM | 0.4759 mL | 2.3794 mL | 4.7587 mL | 11.8968 mL | |
| 15 mM | 0.3172 mL | 1.5862 mL | 3.1725 mL | 7.9312 mL | |
| 20 mM | 0.2379 mL | 1.1897 mL | 2.3794 mL | 5.9484 mL | |
| 25 mM | 0.1903 mL | 0.9517 mL | 1.9035 mL | 4.7587 mL | |
| 30 mM | 0.1586 mL | 0.7931 mL | 1.5862 mL | 3.9656 mL | |
| 40 mM | 0.1190 mL | 0.5948 mL | 1.1897 mL | 2.9742 mL | |
| 50 mM | 0.0952 mL | 0.4759 mL | 0.9517 mL | 2.3794 mL | |
| 60 mM | 0.0793 mL | 0.3966 mL | 0.7931 mL | 1.9828 mL | |
| 80 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4871 mL | |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4759 mL | 1.1897 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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