2,4-Difluorophenol
Based on 1 Customer Validation
2,4-Difluorophenol is a difluoro-substituted phenol that serves as a starting material for the synthesis of 4,6-difluoro-5,7-dihydroxytryptamine.
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- 純度: 99.85%
- CAS 番号: 367-27-1
- 分子式: C6H4F2O
- 分子量:130.09
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MIA PaCa-2 | IC50 |
14758 nM
Compound: S34, r1c11
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Cytotoxicity against human MIA PaCa2 cells after 4 hrs by MTT assay
Cytotoxicity against human MIA PaCa2 cells after 4 hrs by MTT assay
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[PMID: 17944451] |
| MIA PaCa-2 | IC50 |
20772 nM
Compound: S34, r1c11
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Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
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[PMID: 17944451] |
2,4-Difluorophenol microwave spectroscopy and structural analysis confirm only the cis conformer is detectable, with defined rotational, centrifugal distortion, quadrupole coupling, and structural parameters, and an intramolecular hydrogen bond between the hydroxyl H-atom and a fluorine atom with a non-bonded distance of 2.23 Å[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 367-27-1
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性状 Solid
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分子量 130.09
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分子式 C6H4F2O
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Color Colorless to off-white
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SMILES
OC1=CC=C(F)C=C1F
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別名
2,4-ジフルオロフェノール; Phenol, 2,4-difluoro-
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (768.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
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- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.6870 mL | 38.4349 mL | 76.8699 mL | 192.1747 mL |
| 5 mM | 1.5374 mL | 7.6870 mL | 15.3740 mL | 38.4349 mL | |
| 10 mM | 0.7687 mL | 3.8435 mL | 7.6870 mL | 19.2175 mL | |
| 15 mM | 0.5125 mL | 2.5623 mL | 5.1247 mL | 12.8116 mL | |
| 20 mM | 0.3843 mL | 1.9217 mL | 3.8435 mL | 9.6087 mL | |
| 25 mM | 0.3075 mL | 1.5374 mL | 3.0748 mL | 7.6870 mL | |
| 30 mM | 0.2562 mL | 1.2812 mL | 2.5623 mL | 6.4058 mL | |
| 40 mM | 0.1922 mL | 0.9609 mL | 1.9217 mL | 4.8044 mL | |
| 50 mM | 0.1537 mL | 0.7687 mL | 1.5374 mL | 3.8435 mL | |
| 60 mM | 0.1281 mL | 0.6406 mL | 1.2812 mL | 3.2029 mL | |
| 80 mM | 0.0961 mL | 0.4804 mL | 0.9609 mL | 2.4022 mL | |
| 100 mM | 0.0769 mL | 0.3843 mL | 0.7687 mL | 1.9217 mL |
2,4-Difluorophenol 関連分類
HY-W012725 関連分類
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- 2,4-Difluorophenol
- 367-27-1
- Biochemical Assay Reagents
- Drug Intermediate
- quadrupole coupling parameters
- structural analysis
- rotational parameters
- centrifugal distortion parameters
- fluorine atom
- intramolecular hydrogen bond
- cis conformer
- microwave spectroscopy
- structural parameters
- hydroxyl H-atom
- Inhibitor
- inhibitor
- inhibit