98N12-5
Based on 1 publication(s) in Google Scholar
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 917572-74-8
- 分子式: C81H163N9O5
- 分子量:1343.22
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 98N12-5
More
生物活性
化学情報
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CAS 番号 917572-74-8
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性状 Solid
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分子量 1343.22
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分子式 C81H163N9O5
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Color Off-white to light yellow
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SMILES
CCCCCCCCCCCCNC(CCN(CCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)CCNCCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2026 Mar 24:e17931. PMID: 41875360
溶剤 & 溶解度
THF : 50 mg/mL (37.22 mM; Need ultrasonic)
DMSO : 50 mg/mL (37.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Akinc A, Goldberg M, Qin J, et al. Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol Ther. 2009;17(5):872-879. [Content Brief]
[2]. Nguyen DN, Chen SC, Lu J, et al. Drug delivery-mediated control of RNA immunostimulation. Mol Ther. 2009;17(9):1555-1562. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| THF / DMSO | 1 mM | 0.7445 mL | 3.7224 mL | 7.4448 mL | 18.6120 mL |
| 5 mM | 0.1489 mL | 0.7445 mL | 1.4890 mL | 3.7224 mL | |
| 10 mM | 0.0744 mL | 0.3722 mL | 0.7445 mL | 1.8612 mL | |
| 15 mM | 0.0496 mL | 0.2482 mL | 0.4963 mL | 1.2408 mL | |
| 20 mM | 0.0372 mL | 0.1861 mL | 0.3722 mL | 0.9306 mL | |
| 25 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7445 mL | |
| 30 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.6204 mL |
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