Hydroxycotinine
Based on 1 Customer Validation
Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.13%
- CAS 番号: 34834-67-8
- 分子式: C10H12N2O2
- 分子量:192.22
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-B1178
CotinineEndogenous Metabolite -
HY-129692
WithanoneiGluR Inhibitor -
HY-113093S
Ethyl glucuronide-d5Stable Isotope -
HY-B1178R
Cotinine (Standard)Endogenous Metabolite -
HY-D0958
Methylene blue hydratesGC Inhibitor -
HY-W017464
NAPQIAcetaminophen Metabolite -
HY-160236
3-(3-Sulfooxyphenyl)propanoic acidMetabolite of Echinacoside -
HY-W016221
6-Hydroxy ChlorzoxazoneChlorzoxazone Metabolite -
HY-W009247
N-DesmethylolanzapineAntipsychotic Agent -
HY-114992
2-Propyl-2-pentenoic acidValproic Acid Metabolite -
HY-118774
Propofol β-D-glucuronideMetabolite -
HY-G0021S
N-Desmethylclozapine-d8Stable Isotope
生物活性
製品説明
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 34834-67-8
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性状 Solid
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分子量 192.22
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分子式 C10H12N2O2
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Color White to off-white
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SMILES
O=C1N(C)[C@H](C2=CC=CN=C2)C[C@H]1O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 30 mg/mL (156.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2024 mL | 26.0119 mL | 52.0237 mL | 130.0593 mL |
| 5 mM | 1.0405 mL | 5.2024 mL | 10.4047 mL | 26.0119 mL | |
| 10 mM | 0.5202 mL | 2.6012 mL | 5.2024 mL | 13.0059 mL | |
| 15 mM | 0.3468 mL | 1.7341 mL | 3.4682 mL | 8.6706 mL | |
| 20 mM | 0.2601 mL | 1.3006 mL | 2.6012 mL | 6.5030 mL | |
| 25 mM | 0.2081 mL | 1.0405 mL | 2.0809 mL | 5.2024 mL | |
| 30 mM | 0.1734 mL | 0.8671 mL | 1.7341 mL | 4.3353 mL | |
| 40 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2515 mL | |
| 50 mM | 0.1040 mL | 0.5202 mL | 1.0405 mL | 2.6012 mL | |
| 60 mM | 0.0867 mL | 0.4335 mL | 0.8671 mL | 2.1677 mL | |
| 80 mM | 0.0650 mL | 0.3251 mL | 0.6503 mL | 1.6257 mL | |
| 100 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3006 mL |
Hydroxycotinine 関連分類
HY-113239 関連分類
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