Speract
Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
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- CAS 番号: 76901-59-2
- 分子式: C38H57N11O14
- 分子量:891.92
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Speract is a decapeptide from the outer jelly layer of theStrongylocentrotus purpuratus egg that upon binding to its receptor in the sperm, stimulates sperm motility, respiration and ion fluxes, among other physiological events. Speract increases NADH levels and depolarizes the sea urchin sperm mitochondrion[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 76901-59-2
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分子量 891.92
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分子式 C38H57N11O14
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配列
Gly-Phe-Asp-Leu-Asn-Gly-Gly-Gly-Val-Gly
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シーケンスの短縮
GFDLNGGGVG
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Sperm Thawing for Functional Recovery
Sperm thawing for functional recovery is a post-cryopreservation procedure designed to restore and measure sperm motility, viability, membrane/acrosome integrity, DNA integrity, and usable motile sperm yield after freezing-induced injury; published human studies show that cryopreservation reduces motility and viability and can damage the plasmalemma, acrosome, tail, and DNA integrity. The experimental readout is generated by comparing post-thaw motility recovery, viability, acrosomal status, DNA integrity, and recovered motile sperm after thawing and optional sperm-selection steps; thawing at 40°C improved motility recovery compared with 20-37°C without significant differences in viability, ATP content, acrosomal status, or DNA integrity in one human donor-semen study.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)