ABC transporter modulator-3
Based on 1 Customer Validation
ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC50 < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 3093661-88-9
- 分子式: C24H21ClN4O3S
- 分子量:480.97
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
ABC transporter modulator-3 potently increases the expression level of ABCC6 WT, with an EC50 < 1 μM[1].
ABC transporter modulator-3 fails to effectively upregulate the expression of ABCB4 WT, with an EC50 ≥ 25 μM[1].
ABC transporter modulator-3 fails to effectively increase the expression level of ABCA4P1380L, with an EC50 ≥ 25 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3093661-88-9
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性状 Solid
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分子量 480.97
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分子式 C24H21ClN4O3S
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Color White to off-white
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SMILES
O=S(NC1=CC=C(C2=CN=CC(Cl)=C2)N=C1OC3=C(C)C=C(C)C=C3C)(C4=CC=CN=C4)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 51 mg/mL (106.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0791 mL | 10.3957 mL | 20.7913 mL | 51.9783 mL |
| 5 mM | 0.4158 mL | 2.0791 mL | 4.1583 mL | 10.3957 mL | |
| 10 mM | 0.2079 mL | 1.0396 mL | 2.0791 mL | 5.1978 mL | |
| 15 mM | 0.1386 mL | 0.6930 mL | 1.3861 mL | 3.4652 mL | |
| 20 mM | 0.1040 mL | 0.5198 mL | 1.0396 mL | 2.5989 mL | |
| 25 mM | 0.0832 mL | 0.4158 mL | 0.8317 mL | 2.0791 mL | |
| 30 mM | 0.0693 mL | 0.3465 mL | 0.6930 mL | 1.7326 mL | |
| 40 mM | 0.0520 mL | 0.2599 mL | 0.5198 mL | 1.2995 mL | |
| 50 mM | 0.0416 mL | 0.2079 mL | 0.4158 mL | 1.0396 mL | |
| 60 mM | 0.0347 mL | 0.1733 mL | 0.3465 mL | 0.8663 mL | |
| 80 mM | 0.0260 mL | 0.1299 mL | 0.2599 mL | 0.6497 mL | |
| 100 mM | 0.0208 mL | 0.1040 mL | 0.2079 mL | 0.5198 mL |
ABC transporter modulator-3 関連分類
HY-183034 関連分類
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