Acetylcorynoline
Based on 1 Customer Validation
Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.47%
- CAS 番号: 18797-80-3
- 分子式: C23H23NO6
- 分子量:409.43
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Mass Spectrometry Natural Product Library
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Natural Product and Natural Product-Like Compound Library
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Immunology/Inflammation Compound Library
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Natural Product Library
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生物活性
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Cell Line
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Type | Value | Description | References |
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| RAW264.7 | IC50 |
23.1 μM
Compound: 7
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Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS induced nitric oxide production preincubated for 2 hrs followed by LPS challenge measured after 24 hrs by Griess reagent based assay
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS induced nitric oxide production preincubated for 2 hrs followed by LPS challenge measured after 24 hrs by Griess reagent based assay
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[PMID: 29853329] |
Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1].
Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 18797-80-3
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性状 Solid
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分子量 409.43
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分子式 C23H23NO6
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Color Off-white to light yellow
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SMILES
CN1[C@]2([H])C(C(C[C@H](OC(C)=O)[C@]2(C)C3=C(C4=C(OCO4)C=C3)C1)=C5)=CC6=C5OCO6
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 25 mg/mL (61.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4424 mL | 12.2121 mL | 24.4242 mL | 61.0605 mL |
| 5 mM | 0.4885 mL | 2.4424 mL | 4.8848 mL | 12.2121 mL | |
| 10 mM | 0.2442 mL | 1.2212 mL | 2.4424 mL | 6.1060 mL | |
| 15 mM | 0.1628 mL | 0.8141 mL | 1.6283 mL | 4.0707 mL | |
| 20 mM | 0.1221 mL | 0.6106 mL | 1.2212 mL | 3.0530 mL | |
| 25 mM | 0.0977 mL | 0.4885 mL | 0.9770 mL | 2.4424 mL | |
| 30 mM | 0.0814 mL | 0.4071 mL | 0.8141 mL | 2.0353 mL | |
| 40 mM | 0.0611 mL | 0.3053 mL | 0.6106 mL | 1.5265 mL | |
| 50 mM | 0.0488 mL | 0.2442 mL | 0.4885 mL | 1.2212 mL | |
| 60 mM | 0.0407 mL | 0.2035 mL | 0.4071 mL | 1.0177 mL |
Acetylcorynoline 関連分類
HY-N0759 関連分類
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