Anticancer agent 182
Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 133342-90-2
- 分子式: C18H20O5
- 分子量:316.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BC1 cell line | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human BC1 cells
Cytotoxicity against human BC1 cells
|
[PMID: 2045815] |
| Col2 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Col2 cells
Cytotoxicity against human Col2 cells
|
[PMID: 2045815] |
| HT-1080 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 2045815] |
| KB | ED50 |
13.3 μg/mL
Compound: 1
|
Cytotoxicity against vincristine-resistant human KB cells
Cytotoxicity against vincristine-resistant human KB cells
|
[PMID: 2045815] |
| KB | ED50 |
9.4 μg/mL
Compound: 1
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 2045815] |
| Lu1 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
|
[PMID: 2045815] |
| P388 | ED50 |
5.9 μg/mL
Compound: 1
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 2045815] |
| SK-MEL-2 | ED50 |
14.6 μg/mL
Compound: 1
|
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
|
[PMID: 2045815] |
化学情報
-
CAS 番号 133342-90-2
-
分子量 316.35
-
分子式 C18H20O5
-
SMILES
OC1=CC([C@@H]2CCC3=CC=C(OC)C=C3O2)=CC(OC)=C1OC
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)