Anticancer agent 9
Based on 1 Customer Validation
Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.58%
- CAS 番号: 592542-61-5
- 分子式: C22H27NO8S
- 分子量:465.52
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
0.1 μM
Compound: 26a
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Cytotoxicity against human DU145 cells after 96 hrs by trypan blue exclusion assay
Cytotoxicity against human DU145 cells after 96 hrs by trypan blue exclusion assay
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[PMID: 21812421] |
| K562 | IC50 |
0.1 μM
Compound: 26a
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Cytotoxicity against human K562 cells after 96 hrs by trypan blue exclusion assay
Cytotoxicity against human K562 cells after 96 hrs by trypan blue exclusion assay
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[PMID: 21812421] |
Anticancer agent 9 (compound 24) (96 h) inhibits the cell growth, with IC50s of 0.1 μM and 0.1 μM for K562 and DU145 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 592542-61-5
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性状 Solid
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分子量 465.52
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分子式 C22H27NO8S
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Color Off-white to light yellow
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SMILES
O=C(OC)CNC1=CC(CS(=O)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O)=CC=C1OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : 50 mg/mL (107.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1481 mL | 10.7407 mL | 21.4814 mL | 53.7034 mL |
| 5 mM | 0.4296 mL | 2.1481 mL | 4.2963 mL | 10.7407 mL | |
| 10 mM | 0.2148 mL | 1.0741 mL | 2.1481 mL | 5.3703 mL | |
| 15 mM | 0.1432 mL | 0.7160 mL | 1.4321 mL | 3.5802 mL | |
| 20 mM | 0.1074 mL | 0.5370 mL | 1.0741 mL | 2.6852 mL | |
| 25 mM | 0.0859 mL | 0.4296 mL | 0.8593 mL | 2.1481 mL | |
| 30 mM | 0.0716 mL | 0.3580 mL | 0.7160 mL | 1.7901 mL | |
| 40 mM | 0.0537 mL | 0.2685 mL | 0.5370 mL | 1.3426 mL | |
| 50 mM | 0.0430 mL | 0.2148 mL | 0.4296 mL | 1.0741 mL | |
| 60 mM | 0.0358 mL | 0.1790 mL | 0.3580 mL | 0.8951 mL | |
| 80 mM | 0.0269 mL | 0.1343 mL | 0.2685 mL | 0.6713 mL | |
| 100 mM | 0.0215 mL | 0.1074 mL | 0.2148 mL | 0.5370 mL |
Anticancer agent 9 関連分類
HY-78884 関連分類
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