Antitumor agent-41
Antitumor agent-41 (compound N-12), a potent antitumor agent, enhibits excellent antimigration and anti-invasion activity. Antitumor agent-41 (compound N-12) induces tumor inhibition via tumor necrosis and inflammatory response.
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- CAS 番号: 3035564-55-4
- 分子式: C64H109IN2O21
- 分子量:1369.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
>200 μM
Compound: N-12
|
Cytotoxicity against human A-431 cells measured after 24 hrs by MTT assay
Cytotoxicity against human A-431 cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
| CHO | IC50 |
>200 μM
Compound: N-12
|
Cytotoxicity against CHO cells measured after 24 hrs by MTT assay
Cytotoxicity against CHO cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
| HeLa | IC50 |
>200 μM
Compound: N-12
|
Cytotoxicity against human HeLa cells measured after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
| N2a | IC50 |
>200 μM
Compound: N-12
|
Cytotoxicity against mouse Neuro2a cells measured after 24 hrs by MTT assay
Cytotoxicity against mouse Neuro2a cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
| PC-12 | IC50 |
>200 μM
Compound: N-12
|
Cytotoxicity against rat PC-12 cells measured after 24 hrs by MTT assay
Cytotoxicity against rat PC-12 cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
Antitumor agent-41 (compound N-12) has obvious inhibitory activity on invasion at a concentration of 50 μM on A431 cell, and the inhibition rate was 36.6 ± 13.9% [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3035564-55-4
-
分子量 1369.46
-
分子式 C64H109IN2O21
-
SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2CO)OC[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)NC(CCCCCCCCCCCCCCCCC)=O)O)O)O)O[C@@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(C4=CC(I)=CC=C4)=O)O)C(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)