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United States

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製品番号: HY-105721

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Aranotin

Aranotin strongly binds to Nsp15 viral protein. Aranotin can be used as promising SARS-CoV-2 replication strong inhibitor. Aranotin has the potential for COVID-19 research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 19885-51-9
分子式: C₂₀H₁₈N₂O₇S₂
分子量:462.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Aranotin 構造式

CAS 番号: 19885-51-9

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Aranotin strongly binds to Nsp15 viral protein. Aranotin can be used as promising SARS-CoV-2 replication strong inhibitor. Aranotin has the potential for COVID-19 research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
ASPC1	IC₅₀	11 μM Compound: 5	Cytotoxicity against human ASPC1 cells by SRB method Cytotoxicity against human ASPC1 cells by SRB method	[PMID: 37807846]
H69AR	IC₅₀	1.7 μM Compound: 5	Cytotoxicity against human NCI-H69AR cells by SRB method Cytotoxicity against human NCI-H69AR cells by SRB method	[PMID: 37807846]
K562	IC₅₀	1.4 μM Compound: 5	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 37807846]
L02	IC₅₀	16 μM Compound: 5	Cytotoxicity against human L02 cells by SRB method Cytotoxicity against human L02 cells by SRB method	[PMID: 37807846]
MDA-MB-231	IC₅₀	0.7 μM Compound: 5	Cytotoxicity against human MDA-MB-231 cells by SRB method Cytotoxicity against human MDA-MB-231 cells by SRB method	[PMID: 37807846]

化学情報

CAS 番号 19885-51-9
分子量 462.50
分子式 C₂₀H₁₈N₂O₇S₂
SMILES

O=C(N1[C@@]2([H])C3=COC=C[C@@H]2O)[C@@](C4)(SS[C@]1(C3)C5=O)N5[C@@]6([H])C4=COC=C[C@@H]6OC(C)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (276 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Suresh Kumar, et al. Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus replication. Phytomedicine. 2021 May:85:153317. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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