BG-NH2
Based on 1 Customer Validation
BG-NH2 (SNAP-NH2) is an O6-alkylguanine cofactor and an amine-terminated building block. BG-NH2 serves as a key intermediate for the synthesis of various functionalized SNAP-tag fluorescent/functional substrates.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.13%
- CAS 番号: 674799-96-3
- 分子式: C13H14N6O
- 分子量:270.30
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
製品説明
体外実験
BG-NH2 and its derivatives undergo specific, covalent reactions with SNAP-tag proteins or SNAPR ribozymes. Since the amino group on BG-NH2 serves as a universal conjugation site, researchers can conveniently conjugate any molecule containing an NHS ester or other amine-reactive group (such as fluorescent dyes of different wavelengths, biotin, crosslinkers, click chemistry handles, etc.) to it, thus rapidly constructing a large library of SNAP-tag/SNAPR substrates[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 674799-96-3
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性状 Solid
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分子量 270.30
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分子式 C13H14N6O
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Color White to off-white
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SMILES
NCC1=CC=C(COC2=NC(N)=NC3=C2NC=N3)C=C1
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別名
SNAP-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 5 mg/mL (18.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (282 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6996 mL | 18.4980 mL | 36.9959 mL | 92.4898 mL |
| 5 mM | 0.7399 mL | 3.6996 mL | 7.3992 mL | 18.4980 mL | |
| 10 mM | 0.3700 mL | 1.8498 mL | 3.6996 mL | 9.2490 mL | |
| 15 mM | 0.2466 mL | 1.2332 mL | 2.4664 mL | 6.1660 mL |
Keywords
- BG-NH2
- 674799-96-3
- SNAP-NH2
- Drug Intermediate
- near-infrared fluorescent substrates
- O6-alkylguanine cofactor
- DBCO-functionalized benzylguanine cofactors
- ovarian adenocarcinoma
- breast adenocarcinoma
- AzNP-functionalized benzylguanine cofactors
- amine-terminated benzylguanine building block
- MTR1 (SNAPR) ribozyme
- SNAP-tag
- Inhibitor
- inhibitor
- inhibit