Bis-PEG2000-COOH
Based on 1 Customer Validation
Bis-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and surface modification reagent with hydrophilic, biocompatible properties. Bis-PEG2000-COOH coats superparamagnetic iron oxide nanoparticles to prepare carriers for conjugating antigen p210 and adjuvant CpG oligodeoxynucleotides in nanovaccine formulation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子量:2000 (Average)
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Bis-PEG2000-COOH (60 mg; 12 h) successfully modifies Fe3O4@OA nanoparticles to form Fe3O4@DA-PEG[1].
Bis-PEG2000-COOH (100 mg; 24 h) successfully grafts to amino-functionalized SED-150 long afterglow nanospheres[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Powder
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分子量 2000 (Average)
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SMILES
OC(CCOCCC(O)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
純度とドキュメンテーション
参考文献
[1]. Fernandes S, et al. Magnetic Nanoparticle-Based Hyperthermia Mediates Drug Delivery and Impairs the Tumorigenic Capacity of Quiescent Colorectal Cancer Stem Cells. ACS Appl Mater Interfaces. 2021 Apr 14;13(14):15959-15972. [Content Brief]
[3]. Zhang L, et al. A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models. Nat Commun. 2025;16(1):2111. Published 2025 Mar 2. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)