Capuride
Capuride is an orally active sedative agent. Capuride has anticonvulsant activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 5579-13-5
- 分子式: C9H18N2O2
- 分子量:186.25
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体内実験
Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2].
Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electrically (MES) and chemically (scMet) induced seizures in rats[2]
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Dosage:38-107 mg/kg
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Administration:Oral administration (p.o.)
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Result:ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model).
化学情報
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CAS 番号 5579-13-5
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分子量 186.25
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分子式 C9H18N2O2
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SMILES
CCC(C(C(NC(N)=O)=O)CC)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Goldstein L, et al. Quantitative EEG analysis of single-dose effect relationships in normal volunteers of Pacinox (capuride), a new antianxiety drug. Biological psychiatry, 1971, 3(2): 165-172. [Content Brief]
[2]. Jakob Avi Shimshoni, et al. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13;50(25):6419-27. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Capuride 関連分類
HY-119461 関連分類
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