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United States

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製品番号: HY-119524

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Clofibride

Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 26717-47-5
分子式: C₁₆H₂₂ClNO₄
分子量:327.80

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Clofibride 構造式

CAS 番号: 26717-47-5

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体内実験

Clofibride (oral, 400; 500 and 1000 mg/kg; single) can rapidly and massively resorb and hydrolys into 4chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male CD rats, male and female beagles, olive baboon monkeys^[1]
Dosage:

400, 1000 mg/kg (rats); 500 mg/kg (dogs and monkeys)
Administration:

oral, single
Result:

HMB is rapidly metabolized and the half-life of CPIB, the main active metabolite, in the serum is about 12 h in the rat, 43 +9 h in the dog and 6t 1 h in the baboon.

化学情報

CAS 番号 26717-47-5
分子量 327.80
分子式 C₁₆H₂₂ClNO₄
SMILES

CC(OC1=CC=C(C=C1)Cl)(C(OCCCC(N(C)C)=O)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. G P Loiseau, et al. On the metabolism of clofibride, a hypolipaemic drug. J Pharm Pharmacol. 1980 Jul;32(7):483-8. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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