Clorofene
Based on 1 Customer Validation
Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide fungicide widely used in hospitals and homes as a broad-spectrum fungicide in general cleaning and disinfection disinfectant solutions and in soap formulations. Clorofene has antibacterial and carcinogenic activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.09%
- CAS 番号: 120-32-1
- 分子式: C13H11ClO
- 分子量:218.68
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
化学情報
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CAS 番号 120-32-1
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性状 Solid
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分子量 218.68
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分子式 C13H11ClO
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Color Light yellow to orange
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SMILES
OC1=CC=C(C=C1CC2=CC=CC=C2)Cl
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別名
2-Benzyl-4-chlorophenol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (228.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
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データシート (271 KB)
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SDS (923 KB)
- English - EN (923 KB)
- Français - FR (923 KB)
- Deutsch - DE (923 KB)
- Norwegian - NO (923 KB)
- Español - ES (923 KB)
- Swedish - SV (923 KB)
- Italian - IT (923 KB)
- Korean - KR (923 KB)
- Portuguese - PT (923 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of o-Benzyl-p-Chlorophenol (CAS No. 120-32-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Natl Toxicol Program Tech Rep Ser. 1994 Jan;424:1-304. [Content Brief]
[2]. Moore SL, et al. Identification, library synthesis and anti-vibriosis activity of 2-benzyl-4-chlorophenol from cultures of the marine bacterium Shewanella halifaxensis. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3086-3088. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5729 mL | 22.8645 mL | 45.7289 mL | 114.3223 mL |
| 5 mM | 0.9146 mL | 4.5729 mL | 9.1458 mL | 22.8645 mL | |
| 10 mM | 0.4573 mL | 2.2864 mL | 4.5729 mL | 11.4322 mL | |
| 15 mM | 0.3049 mL | 1.5243 mL | 3.0486 mL | 7.6215 mL | |
| 20 mM | 0.2286 mL | 1.1432 mL | 2.2864 mL | 5.7161 mL | |
| 25 mM | 0.1829 mL | 0.9146 mL | 1.8292 mL | 4.5729 mL | |
| 30 mM | 0.1524 mL | 0.7621 mL | 1.5243 mL | 3.8107 mL | |
| 40 mM | 0.1143 mL | 0.5716 mL | 1.1432 mL | 2.8581 mL | |
| 50 mM | 0.0915 mL | 0.4573 mL | 0.9146 mL | 2.2864 mL | |
| 60 mM | 0.0762 mL | 0.3811 mL | 0.7621 mL | 1.9054 mL | |
| 80 mM | 0.0572 mL | 0.2858 mL | 0.5716 mL | 1.4290 mL | |
| 100 mM | 0.0457 mL | 0.2286 mL | 0.4573 mL | 1.1432 mL |