CoelPhos
CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1643661-02-2
- 分子式: C33H33N6O7P
- 分子量:656.62
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
CoelPhos generates a detectable bioluminescent signal in HeLa cells expressing outer membrane-localized GLucM23, with an activity approximately 3-4% of that of native coelenterazine[1].
CoelPhos cannot cross the cell membrane, as it fails to generate a bioluminescent signal in HeLa cells expressing endoplasmic reticulum-localized GLucER[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1643661-02-2
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分子量 656.62
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分子式 C33H33N6O7P
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SMILES
O=C1C(CC2=CC=C(C=C2)OCCCN3N=NC(COCP(O)(O)=O)=C3)=NC4=C(CC5=CC=CC=C5)NC(C6=CC=C(O)C=C6)=CN14
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)