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製品番号: HY-N21645

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Colocynthoside B

Colocynthoside B is a cucurbitane-type triterpenoid glycoside that inhibits passive cutaneous anaphylaxis in type I allergy models and inhibits aflatoxin biosynthesis. Colocynthoside B can be used for research on type I allergy.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 903588-41-0
分子式: C₄₂H₆₂O₁₅
分子量:806.94

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Colocynthoside B 構造式

CAS 番号: 903588-41-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Colocynthoside B (100‑500 µg/mL; 6 days), contained in the chloroform extract, exhibits high anti‑aflatoxigenic activity against Aspergillus flavus Fri2 in CCM medium, with an inhibition rate exceeding 80% at 500 µg/mL^[4].
Colocynthoside B (compound 2) (1 M HCl; 3 h) is a novel cucurbitane-type triterpenoid glycoside isolated from the fruits of Citrullus colocynthis^[2].
Colocynthoside B (500 µg/mL), contained in the chloroform root extract, exhibits the strongest inhibitory effect on aflatoxin accumulation in Aspergillus flavus Fri2 when administered early at 0 h, whereas delayed administration from 65 h onward fails to block mycotoxin biosynthesis^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

化学情報

CAS 番号 903588-41-0
分子量 806.94
分子式 C₄₂H₆₂O₁₅
SMILES

C[C@]12[C@]3([C@](C)([C@]4(C(=CC3)C(C)(C)C(=O)C(O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)=C4)[H])C(=O)C[C@]1(C)[C@@]7([C@@](C2)(O[C@H](/C=C(/CO)\C)C[C@]7(C)O)[H])[H])[H]
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Yoshikawa M, et al. Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis. Chemical & pharmaceutical bulletin. 2007 Mar;55(3):428-34. [Content Brief]

[2]. Darwish RS, et al. Comparative metabolomics reveals the cytotoxic and anti-inflammatory discriminatory chemical markers of raw and roasted colocynth fruit (Citrullus colocynthis L.). RSC Adv. 2021;11(59):37049-37062. Published 2021 Nov 17.

[3]. Degola F, et al. Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins (Basel). 2019 May 22;11(5):286.

[4]. Kapoor M. Citrullus colocynthis an important plant in indian traditional system of medicine. Pharmacognosy Reviews. 2020 Jan 1;14(27):22.

[5]. Dhakad PK. A review on phytochemical studies and biological potential of Citrullus colocynthis (L.) Schrad (Cucurbitaceae). J Bioeng Biosci. 2017;5(4):55-64.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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