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製品番号: HY-187606

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DB293

DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences.

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CAS 番号: 216308-19-9
分子式: C₁₉H₁₆N₆O
分子量:344.37

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

DB293 構造式

CAS 番号: 216308-19-9

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

DB293 (20 μM) forms a cooperative 2:1 dimer with the ATGA sequence and 1:1 monomer complexes with ATATAT and AAATTT sequences, with the highest affinity observed for the ATGA dimer^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 216308-19-9
分子量 344.37
分子式 C₁₉H₁₆N₆O
SMILES

N=C(C1=CC=C(C2=CC=C(C3=NC4=CC=C(C(N)=N)C=C4N3)O2)C=C1)N
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Laughlin S, et al. A novel approach using electrospray ionization mass spectrometry to study competitive binding of small molecules with mixed DNA sequences. Analytical and bioanalytical chemistry. 2014 Oct;406(25):6441-5.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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