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製品番号: HY-N21759

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Dendroside D

Dendroside D is a sesquiterpenoid compound. Dendroside D binds to the RNA site of RNA-dependent RNA polymerase and the active site of SARS-CoV-2 main protease through hydrogen bonds, electrostatic interactions, and hydrophobic interactions, thereby blocking viral replication. Dendroside D stimulates the proliferation of mouse T and B lymphocytes, promotes T and B lymphocyte proliferation, and exhibits immunomodulatory activity. Dendroside D can be used for viral infection and immune-related research.

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CAS 番号: 503443-09-2
分子式: C₂₇H₄₄O₁₄
分子量:592.64

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dendroside D 構造式

CAS 番号: 503443-09-2

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示 :

体外実験

Adaptive ImmunityOthers

Adaptive Immunity

Dendroside D promotes the proliferation of T and B lymphocytes^[3].

Others

Dendroside D exhibits binding affinity to HAase with a docking score of -6.701 Kcal/mol in the molecular docking model^[1].
Dendroside D (15 mg; 7 days) is a glycoside that yields aglycone 1a and glucose upon enzymatic hydrolysis with β-cellulase^[2].
The sugar moiety of Dendroside D (0.04 M; 1 h) is D-glucose, as confirmed by GLC retention time matching authentic D-glucose^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 503443-09-2
分子量 592.64
分子式 C₂₇H₄₄O₁₄
SMILES

C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@@]2(C)[C@@]3([C@]2(CC[C@](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(O)[C@@]5([C@]3([C@H](C)CC5)[H])[H])[H])[H]
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Mohamed EM, et al. Bioassay-Guided Isolation, Metabolic Profiling, and Docking Studies of Hyaluronidase Inhibitors from Ravenala madagascariensis. Molecules. 2020 Apr 8;25(7):1714.

[2]. Ye Q, et al. Immunomodulatory sesquiterpene glycosides from Dendrobium nobile. Phytochemistry. 2002 Dec;61(8):885-90.

[3]. Li J, et al. The Chemical Structure and Pharmacological Activity of Sesquiterpenoids in Dendrobium Sw. Molecules. 2024 Dec 11;29(24):5851.

[4]. Rafli M, et al. Potential of Dendrobium spp. Secondary Metabolites as Medicinal Source for SARS‑CoV‑2. In: Proceedings of the 7th International Conference on Biological Science (ICBS 2021); 2021 Oct 14‑15; Yogyakarta, Indonesia. Advances in Biological Sciences Research. Atlantis Press; 2022.

[5]. Kinasih A, et al In Silico Study of Secondary Metabolites in Dendrobium spp. as SARS‑CoV‑2 Antivirus on Main Protease (Mpro). Jurnal Riset Biologi dan Aplikasinya. 2022 Mar;4(1):19‑25.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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濃度濃度

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分子量分子量

希釈計算機

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濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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生物活性
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- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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Dendroside D

Endogenous Metabolite アイソフォーム固有の製品をすべて表示

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示