DHPCC-9
DHPCC-9 acts as an inhibitor of Pim kinase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1192248-37-5
- 分子式: C15H10N2O
- 分子量:234.25
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
26 μM
Compound: 9
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| Fibroblast | IC50 |
21 μM
Compound: 9
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PA-1 | IC50 |
4.5 μM
Compound: 9
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PC-3 | IC50 |
9.5 μM
Compound: 9
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
化学情報
-
CAS 番号 1192248-37-5
-
分子量 234.25
-
分子式 C15H10N2O
-
SMILES
O=CC1=CNC2=C1C=CC3=C2NC4=C3C=CC=C4
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)