Diproteverine
Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 69373-95-1
- 分子式: C26H35NO4
- 分子量:425.56
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Calcium Channel アイソフォーム固有の製品をすべて表示
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生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley virgin female rats[1]
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Dosage:40, 80, 160, 320 mg/kg
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Administration:P.o.; daily for 10 days
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Result:Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities.
化学情報
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CAS 番号 69373-95-1
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分子量 425.56
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分子式 C26H35NO4
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SMILES
CC(C)OC1=CC2=C(CCN=C2CC3=CC=C(C(OCC)=C3)OCC)C=C1OC(C)C
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別名
BRL 40015
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. [Content Brief]
[2]. Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)