DPhPC
Based on 1 Customer Validation
DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.77%
- CAS 番号: 207131-40-6
- 分子式: C48H96NO8P
- 分子量:846.25
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
DPhPC is the core phospholipid component for constructing nitroglycerin nanoliposomes, which enables the effective encapsulation of nitroglycerin by virtue of its amphipathic property and facilitates the efficient uptake of nanoliposomes by endothelial cells. The nanoliposomes prepared on the basis of DPhPC can improve the bioavailability of nitric oxide and exert anti-inflammatory effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 207131-40-6
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性状 Solid-Liquid Mixture
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分子量 846.25
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分子式 C48H96NO8P
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Color Colorless to light yellow
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SMILES
CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
Ethanol : 50 mg/mL (59.08 mM; Need ultrasonic)
DMSO : 3.57 mg/mL (4.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (645 KB)
- English - EN (645 KB)
- Français - FR (645 KB)
- Deutsch - DE (645 KB)
- Norwegian - NO (645 KB)
- Español - ES (645 KB)
- Swedish - SV (645 KB)
- Italian - IT (645 KB)
- Korean - KR (645 KB)
- Portuguese - PT (645 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Schmidt D, et, al. A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers. J Mol Biol. 2009 Jul 31;390(5):902-12. [Content Brief]
[2]. Andersson M, et, al. Vesicle and bilayer formation of diphytanoylphosphatidylcholine (DPhPC) and diphytanoylphosphatidylethanolamine (DPhPE) mixtures and their bilayers' electrical stability. Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):550-61. [Content Brief]
[3]. Ardekani S, et al. Nanoliposomal nitroglycerin exerts potent anti-inflammatory effects[J]. Scientific reports, 2015, 5(1): 16258. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.1817 mL | 5.9084 mL | 11.8168 mL | 29.5421 mL |
| Ethanol | 5 mM | 0.2363 mL | 1.1817 mL | 2.3634 mL | 5.9084 mL |
| 10 mM | 0.1182 mL | 0.5908 mL | 1.1817 mL | 2.9542 mL | |
| 15 mM | 0.0788 mL | 0.3939 mL | 0.7878 mL | 1.9695 mL | |
| 20 mM | 0.0591 mL | 0.2954 mL | 0.5908 mL | 1.4771 mL | |
| 25 mM | 0.0473 mL | 0.2363 mL | 0.4727 mL | 1.1817 mL | |
| 30 mM | 0.0394 mL | 0.1969 mL | 0.3939 mL | 0.9847 mL | |
| 40 mM | 0.0295 mL | 0.1477 mL | 0.2954 mL | 0.7386 mL | |
| 50 mM | 0.0236 mL | 0.1182 mL | 0.2363 mL | 0.5908 mL |
DPhPC 関連分類
HY-143202 関連分類
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