DPhPC
Based on 1 Customer Validation
DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.77%
- CAS 番号: 207131-40-6
- 分子式: C48H96NO8P
- 分子量:846.25
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
DPhPC is the core phospholipid component for constructing nitroglycerin nanoliposomes, which enables the effective encapsulation of nitroglycerin by virtue of its amphipathic property and facilitates the efficient uptake of nanoliposomes by endothelial cells. The nanoliposomes prepared on the basis of DPhPC can improve the bioavailability of nitric oxide and exert anti-inflammatory effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 207131-40-6
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性状 Oil
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分子量 846.25
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分子式 C48H96NO8P
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Color Colorless to light yellow
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SMILES
CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 3.57 mg/mL (4.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (645 KB)
- English - EN (645 KB)
- Français - FR (645 KB)
- Deutsch - DE (645 KB)
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- Español - ES (645 KB)
- Swedish - SV (645 KB)
- Italian - IT (645 KB)
- Korean - KR (645 KB)
- Portuguese - PT (645 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Schmidt D, et, al. A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers. J Mol Biol. 2009 Jul 31;390(5):902-12. [Content Brief]
[2]. Andersson M, et, al. Vesicle and bilayer formation of diphytanoylphosphatidylcholine (DPhPC) and diphytanoylphosphatidylethanolamine (DPhPE) mixtures and their bilayers' electrical stability. Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):550-61. [Content Brief]
[3]. Ardekani S, et al. Nanoliposomal nitroglycerin exerts potent anti-inflammatory effects[J]. Scientific reports, 2015, 5(1): 16258. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1817 mL | 5.9084 mL | 11.8168 mL | 29.5421 mL |