Elcatonin
Based on 1 Customer Validation
Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 60731-46-6
- 分子式: C148H244N42O47
- 分子量:3363.77
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1]
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Dosage:20 U/kg
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Administration:Subcutaneously; 2 d after oxaliplatin administration
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Result:Attenuated oxaliplatin-induced cold in rtas.
化学情報
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CAS 番号 60731-46-6
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性状 Solid
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分子量 3363.77
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分子式 C148H244N42O47
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別名
Carbocalcitonin
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配列
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Lactam bridge: Ser1-Asu6)
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シーケンスの短縮
SNLST{Asu}VLGKLSQELHKLQTYPRTDVGAGTP-NH2 (Lactam bridge: Ser1-Asu6)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (29.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
参考文献
[1]. Knopp JA, et al. Calcitonin for treating acute pain of osteoporotic vertebral compression fractures: a systematic review of randomized, controlled trials. Osteoporos Int. 2005;16(10):1281‐1290. [Content Brief]
[2]. Aoki M,et al. Comparison of the effects of single doses of elcatonin and pregabalin on oxaliplatin-induced cold and mechanical allodynia in rats. Biol Pharm Bull. 2014;37(2):322‐326. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2973 mL | 1.4864 mL | 2.9729 mL | 7.4321 mL |
| 5 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4864 mL | |
| 10 mM | 0.0297 mL | 0.1486 mL | 0.2973 mL | 0.7432 mL | |
| 15 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4955 mL | |
| 20 mM | 0.0149 mL | 0.0743 mL | 0.1486 mL | 0.3716 mL | |
| 25 mM | 0.0119 mL | 0.0595 mL | 0.1189 mL | 0.2973 mL |
Elcatonin 関連分類
HY-P0007 関連分類
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