Ethotoin
Based on 2 publication(s) in Google Scholar
Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.61%
- CAS 番号: 86-35-1
- 分子式: C11H12N2O2
- 分子量:204.23
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 Ethotoin
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生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Pregnant Sprague-Dawley CD rats[2]
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Dosage:600 mg/kg
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Administration:Oral gavage; 600 mg/kg; once
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Result:Preweaning mortality for Ethotoin was 2.0%, Ethotoin -exposed animals weighed approximately 6.6% less than controls.
化学情報
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CAS 番号 86-35-1
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性状 Solid
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分子量 204.23
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分子式 C11H12N2O2
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Color White to off-white
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SMILES
O=C1N(CC)C(C(C2=CC=CC=C2)N1)=O
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別名
Peganone
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Death Dis
2025 Jun 2;16(1):426. PMID: 40456737 -
Toxicol Lett
Discovery of non-steroidal aldo-keto reductase 1D1 inhibitors through automated screening and in vitro evaluation. [Abstract]2025 Apr:406:31-37. PMID: 39988211
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (489.65 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. A S Troupin, et al. Clinical pharmacology of mephenytoin and ethotoin. Ann Neurol. 1979 Nov;6(5):410-4. [Content Brief]
[2]. D R Minck, et al. Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology. 1991 Apr;43(4):279-93. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8965 mL | 24.4823 mL | 48.9646 mL | 122.4116 mL |
| 5 mM | 0.9793 mL | 4.8965 mL | 9.7929 mL | 24.4823 mL | |
| 10 mM | 0.4896 mL | 2.4482 mL | 4.8965 mL | 12.2412 mL | |
| 15 mM | 0.3264 mL | 1.6322 mL | 3.2643 mL | 8.1608 mL | |
| 20 mM | 0.2448 mL | 1.2241 mL | 2.4482 mL | 6.1206 mL | |
| 25 mM | 0.1959 mL | 0.9793 mL | 1.9586 mL | 4.8965 mL | |
| 30 mM | 0.1632 mL | 0.8161 mL | 1.6322 mL | 4.0804 mL | |
| 40 mM | 0.1224 mL | 0.6121 mL | 1.2241 mL | 3.0603 mL | |
| 50 mM | 0.0979 mL | 0.4896 mL | 0.9793 mL | 2.4482 mL | |
| 60 mM | 0.0816 mL | 0.4080 mL | 0.8161 mL | 2.0402 mL | |
| 80 mM | 0.0612 mL | 0.3060 mL | 0.6121 mL | 1.5301 mL | |
| 100 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2241 mL |
Ethotoin 関連分類
HY-B1642 関連分類
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