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United States

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製品番号: HY-P11933

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FAHF

FAHF is a polypeptide-based dual-signal fluorescent colorimetric probe synthesized by conjugating the 5-carboxyfluorescein (5-FAM) (HY-66022) fluorophore to the Ala-His-Phe-NH₂ tripeptide backbone. FAHF achieves highly selective recognition of Cu²⁺ via fluorescence quenching and colorimetric change. The FAHF-Cu²⁺ complex responds to Glyphosate (HY-B0863) based on the displacement effect, resulting in fluorescence enhancement and a visually distinguishable color change. FAHF can penetrate cell membranes to enable cascade detection of copper (II) and glyphosate in living cells, and it can also be combined with smartphone RGB analysis for semi-quantitative identification.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₃₉H₃₄N₆O₉
分子量:730.72

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

カスタムペプチド

FAHF 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

FAHF (0-30.0 μM) is a selective, reversible, and rapid-response dual-signal probe for detecting Cu²⁺ and Glyphosate (HY-B0863) in 10 mM HEPES buffer (pH 7.4), with a limit of detection of 51.1 nM for Cu²⁺ and 46.8 nM for glyphosate^[1].
FAHF (0-80.0 μM; 24 h) exhibits low cytotoxicity against HaCaT cells, and can be used for cascade fluorescence imaging of Cu²⁺ and Glyphosate in living HaCaT cells^[1].
FAHF enables the detection of Cu²⁺ and Glyphosate in tap water and purified water; test strips based on FAHF allow naked-eye visual detection of Cu²⁺ and Glyphosate under ultraviolet light and natural light^[1].
FAHF (0-5.0 μM) enables smartphone-based RGB analysis for the semi-quantitative detection of Cu²⁺ and glyphosate, with limits of detection of 0.37 μM and 0.52 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HaCaT cells
Concentration:

0, 5.0, 10.0, 20.0, 40.0, 80.0 μM
Incubation Time:

24 h
Result:

Maintained cell viability above 95% across all tested FAHF concentrations after 24 h.

化学情報

分子量 730.72
分子式 C₃₉H₃₄N₆O₉
配列

{FAM}-Ala-His-Phe-NH2
シーケンスの短縮

{FAM}-AHF-NH2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Wang P, et al. A novel peptide‑based fluorometric and colorimetric probe for cascade detection of copper(II) and glyphosate: Applications in real sample, cells imaging, test strips and smartphone‑assisted recognition. Journal of Molecular Structure, 2025, 1328: 141405.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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