Fenarimol
Based on 1 Customer Validation
Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC50 value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.78%
- CAS 番号: 60168-88-9
- 分子式: C17H12Cl2N2O
- 分子量:331.20
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L6 | IC50 |
0.35 μM
Compound: 1
|
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
|
[PMID: 22536986] |
| L6 | IC50 |
76.8 μM
Compound: 1
|
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
|
[PMID: 22536986] |
化学情報
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CAS 番号 60168-88-9
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性状 Solid
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分子量 331.20
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分子式 C17H12Cl2N2O
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Color Off-white to light yellow
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SMILES
ClC1=CC=C(C(C2=CN=CN=C2)(C3=C(Cl)C=CC=C3)O)C=C1
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別名
EL 222
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 10 mg/mL (30.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (623 KB)
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- Italian - IT (623 KB)
- Korean - KR (623 KB)
- Portuguese - PT (623 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0193 mL | 15.0966 mL | 30.1932 mL | 75.4831 mL |
| 5 mM | 0.6039 mL | 3.0193 mL | 6.0386 mL | 15.0966 mL | |
| 10 mM | 0.3019 mL | 1.5097 mL | 3.0193 mL | 7.5483 mL | |
| 15 mM | 0.2013 mL | 1.0064 mL | 2.0129 mL | 5.0322 mL | |
| 20 mM | 0.1510 mL | 0.7548 mL | 1.5097 mL | 3.7742 mL | |
| 25 mM | 0.1208 mL | 0.6039 mL | 1.2077 mL | 3.0193 mL | |
| 30 mM | 0.1006 mL | 0.5032 mL | 1.0064 mL | 2.5161 mL |