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製品番号: HY-N3931

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Gardneramine

Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 34274-91-4
分子式: C₂₃H₂₈N₂O₅
分子量:412.48

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Gardneramine 構造式

CAS 番号: 34274-91-4

容量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Gardneramine (80 μg/mL; 0-20 min) has inhibitory effect on the atria of guinea pigs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Gardneramine (4 mg/kg; i.v.; single dose) leads to a decrease in blood pressure in rabbits (up to 36.6%)^[1].
Gardneramine (0.2 mg/kg, 0.4 mg/kg; i.a.; single dose) increases blood flow rate and produces vasodilation in the hind limbs of dogs^[1].
Gardneramine (20 mg/kg, 40 mg/kg, and 80 mg/kg; i.p.; single dose) inhibits the movement of smooth muscle organs such as the stomach and intestines in mice^[1].
Gardneramine (20 mg/kg; p.o.; single dose) mice were treated with small intestine removal, showing relaxation and slight inhibition of stress ion production^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 34274-91-4
分子量 412.48
分子式 C₂₃H₂₈N₂O₅
SMILES

COC1=C2C34C5N(C/6)[C@@]([C@](COC4=NC2=C(OC)C=C1OC)([H])[C@@](C6=C\COC)([H])C5)([H])C3
Structure Classification
- Alkaloids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Harada M, et al. [Pharmacological studies on gardneria alkaloids. II. Peripheral effects (effects on circulatory and digestive systems)]. Yakugaku Zasshi. 1972 Dec;92(12):1540-6. Japanese. [Content Brief]

Calculators

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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