Ctf1 - cardiotrophin 1 Gene

Predicted to enable cytokine activity and Leukemia Inhibitory Factor receptor binding activity. Acts upstream of or within neuron development. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; gut; and heart and pericardium. Used to study abdominal obesity-metabolic syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CTF1 (cardiotrophin 1). [provided by Alliance of Genome Resources, Apr 2022]