DNAJC15 - DnaJ heat shock protein family (Hsp40) member C15 Gene

Also Known as MCJ; HSD18; DNAJD1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 29103

About DNAJC15

Cytogenetic location: 13q14.11 Genomic coordinates (GRCh38): 13:43,023,586-43,114,213 (from NCBI)

This gene has 2 transcripts (splice variants), 201 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 13.6), small intestine (RPKM 12.6) and 24 other tissues.

Summary

Predicted to enable ATPase activator activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within several processes, including cellular response to starvation; negative regulation of mitochondrial electron transport, NADH to ubiquinone; and negative regulation of protein-containing complex assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC15 Products (1)

mRNA Protein Name
NM_013238.3 NP_037370.2 dnaJ homolog subfamily C member 15

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
23263864 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNAJC15 Protein Structure

DnaJ

DnaJ: DnaJ domain (100 - 149)

  • 0
  • 100
  • 150 a.a.
Protein Preferred Names Protein Names

dnaJ homolog subfamily C member 15

  • DNAJ domain-containing

DNAJC15 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
DNAJC15 Q9Y5T4 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
Intra
DNAJC15 Q9Y5T4 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
DNAJC15 Q9Y5T4 FAM9B Homo sapiens Q8IZU0
Validated Y2H
25416956
Intra
DNAJC15 Q9Y5T4 PAM16 Homo sapiens Q9Y3D7
Anti Tag CoIP
33961781
Intra
DNAJC15 Q9Y5T4 PAM16 Homo sapiens Q9Y3D7
Anti Bait CoIP
23263864
Intra
DNAJC15 Q9Y5T4 PAM16 Homo sapiens Q9Y3D7
Pull Down
23263864
Intra
DNAJC15 Q9Y5T4 SIAH1 Homo sapiens Q8IUQ4
Y2H Array
25416956
Intra
DNAJC15 Q9Y5T4 SIAH1 Homo sapiens Q8IUQ4
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

DNAJC15 抗体

製品番号 製品名 アプリケーション 反応性
HY-P83237 MCJ Antibody (YA2982) WB, IHC-P Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS03878 DNAJC15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29505 Dnajc15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus DNAJC15 VGNC VGNC:53812
Felis catus DNAJC15 VGNC VGNC:102185
Rattus norvegicus DNAJC15 RGD RGD:1307154
Mus musculus DNAJC15 MGD MGI:1913398
Macaca mulatta DNAJC15 VGNC VGNC:106258
Others DNAJC15 NCBI