Lbh - limb-bud and heart Gene

Also Known as 1810009F10Rik; 6720416L16Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 77889

Summary

Involved in several processes, including negative regulation of intracellular Estrogen receptor signaling pathway; positive regulation of mammary stem cell proliferation; and positive regulation of somatic stem cell division. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including gut; heart; limb bud; mesendoderm; and nervous system. Orthologous to human LBH (LBH regulator of Wnt signaling pathway). [provided by Alliance of Genome Resources, Apr 2022]

Lbh Products (1)

mRNA Protein Name
NM_029999.4 NP_084275.3 protein LBH

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence 参考文献 由来
involved in mammary gland development IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in mammary gland epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in negative regulation of intracellular estrogen receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in negative regulation of stem cell differentiation IMP
IMP: Inferred from mutant phenotype
25655704 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11336496 MGI
involved in positive regulation of mammary stem cell proliferation IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in positive regulation of somatic stem cell division IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in positive regulation of somatic stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
25655704 MGI
involved in regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25655704 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in nucleus IDA
IDA: Inferred from direct assay
11336496 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein LBH

  • limb bud and heart-expressed protein

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
製品番号 製品名 製品効果
純度 Rare Diseases
HY-10224 Panobinostat 99.37% Yes
HY-10224A Panobinostat lactate 98.67% Yes

Pre-clinical Phase

Bioactive Molecules (6)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-10224R Panobinostat (Standard) 98.09% Unkown
HY-10224S Panobinostat-d4 / Unkown
HY-10224S1 Panobinostat-d4 hydrochloride / Unkown
HY-RS07542 LBH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20682 Lbh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27193 Lbh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Lbh NCBI NCBI:81606