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GSK951

GSK951 is a potent and selective Kallikrein-5 (KLK5) inhibitor amenable to epidermal delivery. GSK951 shows an IC50 of 250 pM for KLK5 and greater than 100-fold selectivity over KLK7 and KLK14. GSK951 can reduce transepidermal water loss, and decrease proinflammatory cytokine expression. GSK951 can be used for the researches of inflammation and immunology, such as Netherton syndrome.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • CAS 番号: 2393881-77-9
  • 分子式: C22H19BF3N3O3
  • 分子量:441.21
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • GSK951 Chemical Structure
    GSK951 構造式
CAS 番号: 2393881-77-9
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    GSK951 Chemical Structure
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  • GSK951