HD-800
HD-800 is a tubulin inhibitor with an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. HD-800 can be used to generate a radioactive tracer [11C]HD-800, and [11C]HD-800 can penetrate the blood-brain barrier and be used for positron emission tomography (PET) in various neurological diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1204408-27-4
- 分子式: C15H15N3O2
- 分子量:269.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | GI50 |
10 nM
Compound: 3
|
Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27213719] |
化学情報
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CAS 番号 1204408-27-4
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分子量 269.30
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分子式 C15H15N3O2
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SMILES
N=1C=NC(=C2C1OC=C2C)N(C3=CC=C(OC)C=C3)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)