HOPan
Based on 3 publication(s) in Google Scholar
HOPan is a PanK substrate and Pantothenate (HY-B0430) analog. HOPan inhibits CoA levels.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 18679-90-8
- 分子式: C10H19NO5
- 分子量:233.26
-
保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 HOPan
More
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 18679-90-8
-
性状 Oil
-
分子量 233.26
-
分子式 C10H19NO5
-
Color Colorless to light yellow
-
SMILES
OCC(C)(C)[C@@H](O)C(NCCCC(O)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
-
Journal Impact Factor
-
Most Recent
-
Antioxidants (Basel)
2026 May 9;15(5):600. PMID: 42193221 -
Aging Cell
HLH-30/TFEB Rewires the Chaperone Network to Promote Proteostasis Upon Perturbations to the Coenzyme A and Iron-Sulfur Cluster Biosynthesis Pathways. [Abstract]2025 Jun;24(6):e70038. PMID: 40304211 -
溶剤 & 溶解度
H2O : 100 mg/mL (428.71 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (270 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. [Content Brief]
[2]. Ma Y, et al. Highly selective DNA aptamer sensor for intracellular detection of coenzyme A. Chem Sci. 2025 Mar 28;16(18):8023-8029. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.2871 mL | 21.4353 mL | 42.8706 mL | 107.1765 mL |
| 5 mM | 0.8574 mL | 4.2871 mL | 8.5741 mL | 21.4353 mL | |
| 10 mM | 0.4287 mL | 2.1435 mL | 4.2871 mL | 10.7177 mL | |
| 15 mM | 0.2858 mL | 1.4290 mL | 2.8580 mL | 7.1451 mL | |
| 20 mM | 0.2144 mL | 1.0718 mL | 2.1435 mL | 5.3588 mL | |
| 25 mM | 0.1715 mL | 0.8574 mL | 1.7148 mL | 4.2871 mL | |
| 30 mM | 0.1429 mL | 0.7145 mL | 1.4290 mL | 3.5726 mL | |
| 40 mM | 0.1072 mL | 0.5359 mL | 1.0718 mL | 2.6794 mL | |
| 50 mM | 0.0857 mL | 0.4287 mL | 0.8574 mL | 2.1435 mL | |
| 60 mM | 0.0715 mL | 0.3573 mL | 0.7145 mL | 1.7863 mL | |
| 80 mM | 0.0536 mL | 0.2679 mL | 0.5359 mL | 1.3397 mL | |
| 100 mM | 0.0429 mL | 0.2144 mL | 0.4287 mL | 1.0718 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
HOPan 関連分類
HY-139729 関連分類
Powered by Bioz