18679-90-8
18679-90-8
Chemical Structure
HOPan
- CAS No.: 18679-90-8
- Formula:C10H19NO5
- Molecular Weight:233.26
IUPAC Name: (R)-4-(2,4-dihydroxy-3,3-dimethylbutanamido)butanoic acid
InChIKey: SBBDHANTMHIRGW-QMMMGPOBSA-N
SMILES: OCC(C)(C)[C@@H](O)C(NCCCC(O)=O)=O
Biological Activity: HOPan is a PanK substrate and Pantothenate (HY-B0430) analog. HOPan inhibits CoA levels[1][2].
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HOPan | HOPan is a PanK substrate and Pantothenate (HY-B0430) analog. HOPan inhibits CoA levels. | |||||||||||||||||||||
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References
- [1]. Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. [Content Brief]
- [2]. Ma Y, et al. Highly selective DNA aptamer sensor for intracellular detection of coenzyme A. Chem Sci. 2025 Mar 28;16(18):8023-8029. [Content Brief]
Keywords
