IDR-HH2
IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1214699-22-5
- 分子式: C62H117N23O13
- 分子量:1392.74
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 1214699-22-5
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分子量 1392.74
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分子式 C62H117N23O13
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配列
Val-Gln-Leu-Arg-Ile-Arg-Val-Ala-Val-Ile-Arg-Ala-NH2
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シーケンスの短縮
VQLRIRVAVIRA-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Madera L, et al. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin[J]. Journal of innate immunity, 2012, 4(5-6): 553-568. [Content Brief]
[2]. Rivas-Santiago B, et al. Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models[J]. PloS one, 2013, 8(3): e59119. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)