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United States

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Total: USD 0.00 Checkout

製品番号: HY-187441

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Insecticidal agent 37

Insecticidal agent 37 is an insecticide with activity against both nymph and adult stages of Aphis fabae. Insecticidal agent 37 exhibits strong binding affinity to the acetylcholine-binding protein of Aplysia californica via forming multiple hydrogen bonds and hydrophobic interactions with key residues.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₁H₁₂ClN₃OS
分子量:389.86

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 37 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Insecticidal agent 37 (compound 10b) binds strongly to the Aplysia californica acetylcholine-binding protein (PDB: 3SQ6) with a binding energy of −7.30 kcal/mol, forming multiple stabilizing hydrogen bonds and hydrophobic interactions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Insecticidal agent 37 (10b) (five different concentrations; dipping method; single exposure; 10 s) exhibits highly efficient aphicidal activity against nymphs of the broad bean aphid, with an LC₅₀ of 0.117 mg/L^[1].
Insecticidal agent 37 (10b) (five different concentrations; dipping method; single exposure; 10 s) exhibits high aphicidal activity against adult *Aphis fabae*, with an LC₅₀ of 0.366 mg/L^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

nymph stage^[1]
Dosage:

five different concentrations
Administration:

immersion; single exposure; 10 s
Result:

Exhibited a median lethal concentration (LC₅₀) of 0.117 mg/L against Aphis fabae nymphs.

Animal Model:

adult stage^[1]
Dosage:

five different concentrations
Administration:

immersion; single exposure; 10 s
Result:

Exhibited a median lethal concentration (LC₅₀) of 0.366 mg/L against Aphis fabae adults.

化学情報

分子量 389.86
分子式 C₂₁H₁₂ClN₃OS
SMILES

N#CC1=C(OC2=C(C1C3=CC=C(C=C3)Cl)SC4=C2C=C5C=CC=CC5=N4)N
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. A Abdul-Malik M, et al. Design, Synthesis, Characterization, Toxicological Effects, and Molecular Docking Insights of Some Novel Quinoline Compounds as Potential Insecticides. ACS omega. 2026 Jul 28;11(29):44526-44537. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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