IPPD-Q
Based on 1 publication(s) in Google Scholar
IPPD-Q is a p-phenylenediamine quinone and also Environmental pollutant. IPPD-Q can be present in tires, fine particulate matter and urban water bodies. IPPD-Q increases the activities of antioxidant enzymes (SOD, CAT), alters photosynthesis and energy metabolism pathways, and changes gene expression and metabolic profiles. IPPD-Q exhibits phytotoxic effects. IPPD-Q shows acute toxicity to zebrafish embryos and reduces their survival rate.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.38%
- CAS 番号: 68054-73-9
- 分子式: C15H16N2O2
- 分子量:256.30
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 IPPD-Q
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生物活性
製品説明
体外実験
IPPD-Q (0.1-1000 μg/L; 21 days) exposure induces concentration-dependent effects on wheat seedlings, reducing shoot length at high concentrations (100, 1000 μg/L), increasing fresh weight at low concentrations (0.1, 1, 10 μg/L), altering osmoprotectant levels, and modulating the uptake of multiple nutrient elements[2].
IPPD-Q (0.1-1000 μg/L; 21 days) exposure enhances photosynthetic pigment levels and stomatal conductance in wheat seedlings, while inducing oxidative stress via increased antioxidant enzyme (SOD, POD, CAT) activities and MDA content, with concentration-dependent effects on photosynthetic gas exchange parameters[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Danio rerio larvae[3]
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Dosage:10 μg/L
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Administration:aqueous exposure; continuous; 96 hours
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Result:Reduced zebrafish embryo survival rate to 73.3% (vs 95.3% in blank control).
Reached a minimum survival rate of 20.7% at 20 minutes of chlorination reaction time, before recovering to 58.7% at 360 minutes.
Reached a minimum survival rate of 40.7% at 30 minutes of chloramination reaction time.
Caused significantly sparser locomotor trajectories in surviving embryos exposed to chlorination transformation products compared to chloramination transformation products or parent IPPD-Q.
Had a predicted 96 h LC50 of 26.174 mg/L, while TP-290-1 (mono-Cl substitution at C2) had a predicted 96 h LC50 of 19.107 mg/L.
化学情報
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CAS 番号 68054-73-9
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性状 Solid
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分子量 256.30
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分子式 C15H16N2O2
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Color Brown to reddish brown
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SMILES
O=C1C(NC(C)C)=CC(C(NC2=CC=CC=C2)=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Environ Pollut
2026 Jul 1:400:128295. PMID: 42105897
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (97.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
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- Italian - IT (537 KB)
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- Portuguese - PT (537 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Wang W, et al. Beyond Substituted -Phenylenediamine Antioxidants: Prevalence of Their Quinone Derivatives in PM. Environmental science & technology. 2022 Aug 02;56(15):10629-10637. [Content Brief]
[3]. Chen H, et al. Mechanistic insights into the transformation and toxicity evolution of IPPD-Q during chlorination and chloramination in drinking water. Water research. 2026 Jan 15;289(Pt A):124884. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9017 mL | 19.5084 mL | 39.0168 mL | 97.5419 mL |
| 5 mM | 0.7803 mL | 3.9017 mL | 7.8034 mL | 19.5084 mL | |
| 10 mM | 0.3902 mL | 1.9508 mL | 3.9017 mL | 9.7542 mL | |
| 15 mM | 0.2601 mL | 1.3006 mL | 2.6011 mL | 6.5028 mL | |
| 20 mM | 0.1951 mL | 0.9754 mL | 1.9508 mL | 4.8771 mL | |
| 25 mM | 0.1561 mL | 0.7803 mL | 1.5607 mL | 3.9017 mL | |
| 30 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2514 mL | |
| 40 mM | 0.0975 mL | 0.4877 mL | 0.9754 mL | 2.4385 mL | |
| 50 mM | 0.0780 mL | 0.3902 mL | 0.7803 mL | 1.9508 mL | |
| 60 mM | 0.0650 mL | 0.3251 mL | 0.6503 mL | 1.6257 mL | |
| 80 mM | 0.0488 mL | 0.2439 mL | 0.4877 mL | 1.2193 mL |
IPPD-Q 関連分類
HY-W754777 関連分類
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